SMAD3 antibody (pSer423, pSer425)

Catalog No. ABIN7603331

This anti-SMAD3 antibody is a Rabbit Monoclonal antibody detecting SMAD3 in WB, IHC, IF and ICC. Suitable for Human and Mouse.

Quick Overview for SMAD3 antibody (pSer423, pSer425) (ABIN7603331)

Target: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SMAD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AHO-19

Product Details anti-SMAD3 Antibody

Binding Specificity: pSer423, pSer425

Purpose: Anti-Phospho-Smad3 (S423 + S425) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-Smad3 ( + ) Rabbit Monoclonal Antibody (ABIN7603331). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-Smad3 (S423 + S425)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for SMAD3

Target: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Alternative Name: SMAD3

Background:

Synonyms: Mothers against decapentaplegic homolog 3,MAD homolog 3,Mad3,Mothers against DPP homolog 3,hMAD-3,JV15-2,SMAD family member 3,SMAD 3,Smad3,hSMAD3,SMAD3,MADH3,

Tissue Specificity: Widely expressed. Isoform 3 is not expressed in the pituitary gland. .

Molecular Weight: 90-100 kDa

UniProt: P84022

Pathways: Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy