MAP3K7 antibody (pSer439)

Catalog No. ABIN7603333

The Rabbit Monoclonal anti-MAP3K7 antibody has been validated for WB and IP. It is suitable to detect MAP3K7 in samples from Human, Mouse and Rat.

Quick Overview for MAP3K7 antibody (pSer439) (ABIN7603333)

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAP3K7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 28M09

Product Details anti-MAP3K7 Antibody

Binding Specificity: pSer439

Purpose: Anti-Phospho-TAK1 (S439) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-TAK1 Rabbit Monoclonal Antibody (ABIN7603333). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-TAK1 (S439)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Alternative Name: MAP3K7

Background:

Synonyms: Tyrosine-protein kinase Lyn,2.7.10.2,Lck/Yes-related novel protein tyrosine kinase,V-yes-1 Yamaguchi sarcoma viral related oncogene homolog,p53Lyn,p56Lyn,LYN,JTK8,

Tissue Specificity: Detected in monocytes (at protein level). Detected in placenta, and in fetal brain, lung, liver and kidney. Widely expressed in a variety of organs, tissues, and cell types such as epidermoid, hematopoietic, and neuronal cells. Expressed in primary neuroblastoma tumors. .

Molecular Weight: 72 kDa

UniProt: O43318

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway