PAK4 antibody (pSer474, pSer560, pSer602)

Catalog No. ABIN7603338

This Rabbit Monoclonal antibody specifically detects PAK4 in WB and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PAK4 antibody (pSer474, pSer560, pSer602) (ABIN7603338)

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PAK4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: ADFF-16

Product Details anti-PAK4 Antibody

Binding Specificity: pSer474, pSer560, pSer602

Purpose: Anti-Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Monoclonal Antibody

Characteristics: Anti-Phospho-PAK4 + PAK5 + PAK6 ( + + ) Monoclonal Antibody (ABIN7603338). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
FC 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Alternative Name: PAK4

Background:

Synonyms: Red fluorescent protein eqFP611,GFP-like chromoprotein,

Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .

Molecular Weight: 15 kDa

Pathways: RTK Signaling