Glycogen Synthase 1 antibody (pSer641)

Catalog No. ABIN7603351

The Rabbit Monoclonal anti-Glycogen Synthase 1 antibody has been validated for WB, IHC, IF, IP and ICC. It is suitable to detect Glycogen Synthase 1 in samples from Human and Mouse.

Quick Overview for Glycogen Synthase 1 antibody (pSer641) (ABIN7603351)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: DCH-7

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: pSer641

Purpose: Anti-Phospho-Glycogen synthase 1 (S641) GYS1 Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-Glycogen synthase 1 GYS1 Rabbit Monoclonal Antibody (ABIN7603351). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-Glycogen synthase 1 (S641)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1

Background:

Synonyms: Glycogen [starch] synthase, muscle,2.4.1.11,GYS1,GYS,

Tissue Specificity: Specifically expressed in immune and hematopoietic cells. Expressed in bone marrow and blood cells. Levels vary considerably within this compartment. Present in at least 74 % of immature CD34+ cells, whereas within the more mature population of CD33+ cells, it is present in only 10 % of cells. Present in the majority of T-cells, while it is present in a minority of B-cells (at protein level). .

Molecular Weight: 40 kDa

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process