LYN antibody (pTyr396)

Catalog No. ABIN7603452

This Rabbit Monoclonal antibody specifically detects LYN in WB, FACS, ICC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for LYN antibody (pTyr396) (ABIN7603452)

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LYN antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: IFI-12

Product Details anti-LYN Antibody

Binding Specificity: pTyr396

Purpose: Anti-Phospho-Lyn (Y396) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-Lyn Rabbit Monoclonal Antibody (ABIN7603452). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-Lyn (Y396)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000
ICC/IF 1:50-1:200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Alternative Name: LYN

Background:

Synonyms: Tyrosine-protein kinase Lyn,2.7.10.2,Lck/Yes-related novel protein tyrosine kinase,V-yes-1 Yamaguchi sarcoma viral related oncogene homolog,p53Lyn,p56Lyn,LYN,JTK8,

Tissue Specificity: Detected in monocytes (at protein level). Detected in placenta, and in fetal brain, lung, liver and kidney. Widely expressed in a variety of organs, tissues, and cell types such as epidermoid, hematopoietic, and neuronal cells. Expressed in primary neuroblastoma tumors. .

Molecular Weight: 130 kDa

UniProt: P07948

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling