CBL antibody (pTyr774)

Catalog No. ABIN7603466

The Rabbit Monoclonal anti-CBL antibody (Clone 28C29) (ABIN7603466) specifically detects CBL in WB, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for CBL antibody (pTyr774) (ABIN7603466)

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CBL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 28C29

Product Details anti-CBL Antibody

Binding Specificity: pTyr774

Purpose: Anti-Phospho-CBL (Y774) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-CBL Rabbit Monoclonal Antibody (ABIN7603466). Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-CBL (Y774)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CBL

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Alternative Name: CBL

Background:

Synonyms: Focal adhesion kinase 1,FADK 1,2.7.10.2,Focal adhesion kinase-related nonkinase,FRNK,Protein phosphatase 1 regulatory subunit 71,PPP1R71,Protein-tyrosine kinase 2,p125FAK,pp125FAK,PTK2,FAK, FAK1,

Tissue Specificity: Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous. .

Molecular Weight: 120 kDa

UniProt: P22681

Pathways: TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals