APAF1 antibody

Catalog No. ABIN7604004

This Rabbit Monoclonal antibody specifically detects APAF1 in WB, IHC, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for APAF1 antibody (ABIN7604004)

Target: APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This APAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: BHF-1

Product Details anti-APAF1 Antibody

Purpose: Anti-APAF1 Rabbit Monoclonal Antibody

Characteristics: Anti-APAF1 Rabbit Monoclonal Antibody (ABIN7604004). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human APAF1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for APAF1

Target: APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))

Alternative Name: APAF1

Background:

Synonyms: Apoptotic protease-activating factor 1,APAF-1,APAF1,KIAA0413,

Tissue Specificity: Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Molecular Weight: 52 kDa

UniProt: O14727

Pathways: p53 Signaling, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity