Aurora Kinase B antibody

Catalog No. ABIN7604079

This Rabbit Monoclonal antibody specifically detects Aurora Kinase B in WB, IHC, IF, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for Aurora Kinase B antibody (ABIN7604079)

Target: Aurora Kinase B (AURKB)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: FA-1

Product Details anti-Aurora Kinase B Antibody

Purpose: Anti-Aurora B AURKB Rabbit Monoclonal Antibody

Characteristics: Anti-Aurora B AURKB Rabbit Monoclonal Antibody (ABIN7604079). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Aurora B

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: AURKB

Background:

Synonyms: Aurora kinase B,2.7.11.1,Aurora 1,Aurora- and IPL1-like midbody-associated protein 1,AIM-1,Aurora/IPL1-related kinase 2,ARK-2,Aurora-related kinase 2,STK-1,Serine/threonine-protein kinase 12,Serine/threonine-protein kinase 5,Serine/threonine-protein kinase aurora-B,AURKB,AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5,

Tissue Specificity: High level expression seen in the thymus. It is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase. .

Molecular Weight: 39 kDa

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades