CD74 antibody

Catalog No. ABIN7604356

The Rabbit Monoclonal anti-CD74 antibody has been validated for FACS, WB, IF, IHC and ICC. It is suitable to detect CD74 in samples from Human.

Quick Overview for CD74 antibody (ABIN7604356)

Target: CD74 (HLA-DR-gamma (CD74))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD74 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: AOIF-3

Product Details anti-CD74 Antibody

Purpose: Anti-CD74 Rabbit Monoclonal Antibody

Characteristics: Anti-CD74 Rabbit Monoclonal Antibody (ABIN7604356). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CD74

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74

Background:

Synonyms: HLA class II histocompatibility antigen gamma chain,HLA-DR antigens-associated invariant chain,Ia antigen-associated invariant chain,Ii,p33,CD74,CD74,DHLAG,

Tissue Specificity: Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .

Molecular Weight: 17 kDa

UniProt: P04233

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints