CHEK2 antibody

Catalog No. ABIN7604430

This Rabbit Monoclonal antibody specifically detects CHEK2 in WB, IHC, IF, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for CHEK2 antibody (ABIN7604430)

Target: CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CHEK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: FOF-3

Product Details anti-CHEK2 Antibody

Purpose: Anti-Chk2 CHEK2 Rabbit Monoclonal Antibody

Characteristics: Anti-Chk2 CHEK2 Rabbit Monoclonal Antibody (ABIN7604430). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Chk2

Isotype: IgG

Application Details

Application Notes: WB 1:10000-1:20000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CHEK2

Target: CHEK2 (Checkpoint Kinase 2 (CHEK2))

Alternative Name: CHEK2

Background:

Synonyms: Serine/threonine-protein kinase Chk2,2.7.11.1,CHK2 checkpoint homolog,Cds1 homolog,Hucds1,hCds1,Checkpoint kinase 2,CHEK2,CDS1, CHK2, RAD53,

Tissue Specificity: High expression is found in testis, spleen, colon and peripheral blood leukocytes. Low expression is found in other tissues.

Molecular Weight: 75 kDa

UniProt: O96017

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle