PARP1 antibody

Catalog No. ABIN7604450

This anti-PARP1 antibody is a Rabbit Monoclonal antibody detecting PARP1 in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for PARP1 antibody (ABIN7604450)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: HI-16

Product Details anti-PARP1 Antibody

Purpose: Anti-Cleaved PARP PARP1 Rabbit Monoclonal Antibody

Characteristics: Anti-Cleaved PARP PARP1 Rabbit Monoclonal Antibody (ABIN7604450). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Cleaved PARP

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP1

Background:

Synonyms: Poly [ADP-ribose] polymerase 1,PARP-1,2.4.2.30,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,NAD (+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,PARP1,ADPRT, PPOL,

Tissue Specificity: Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. .

Molecular Weight: 25 kDa

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location