DDR2 antibody

Catalog No. ABIN7604626

The Rabbit Monoclonal anti-DDR2 antibody has been validated for WB. It is suitable to detect DDR2 in samples from Human, Mouse and Rat.

Quick Overview for DDR2 antibody (ABIN7604626)

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DDR2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACEB-4

Product Details anti-DDR2 Antibody

Purpose: Anti-DDR2 Monoclonal Antibody

Characteristics: Anti-DDR2 Monoclonal Antibody (ABIN7604626). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human DDR2 This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for DDR2

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Alternative Name: DDR2

Background:

Synonyms: Myosin light chain kinase, smooth muscle,MLCK,s mMLCK,2.7.11.18,Kinase-related protein,KRP,Telokin,Myosin light chain kinase, smooth muscle, deglutamylated form,MYLK,MLCK, MLCK1, MYLK1,

Tissue Specificity: Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. Telokin has been found in a wide variety of adult and fetal tissues. Accumulates in well differentiated enterocytes of the intestinal epithelium in response to tumor necrosis factor (TNF). .

UniProt: Q16832

Pathways: RTK Signaling