UBR5 antibody

Catalog No. ABIN7604710

The Rabbit Monoclonal anti-UBR5 antibody is suitable to detect UBR5 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for UBR5 antibody (ABIN7604710)

Target: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UBR5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 24U00

Product Details anti-UBR5 Antibody

Purpose: Anti-EDD Rabbit Monoclonal Antibody

Characteristics: Anti-EDD Rabbit Monoclonal Antibody (ABIN7604710). Tested in WB application. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human EDD

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for UBR5

Target: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Alternative Name: UBR5

Background:

Synonyms: Clathrin heavy chain 1,Clathrin heavy chain on chromosome 17,CLH-17,CLTC,CLH17, CLTCL2, KIAA0034,

Tissue Specificity: In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

Molecular Weight: 309 kDa

UniProt: O95071

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway