FGFR3 antibody

Catalog No. ABIN7604843

This anti-FGFR3 antibody is a Rabbit Monoclonal antibody detecting FGFR3 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for FGFR3 antibody (ABIN7604843)

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FGFR3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AAID-6

Product Details anti-FGFR3 Antibody

Purpose: Anti-FGFR3 Rabbit Monoclonal Antibody

Characteristics: Anti-FGFR3 Rabbit Monoclonal Antibody (ABIN7604843). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human FGFR3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Alternative Name: FGFR3

Background:

Synonyms: Fibroblast growth factor receptor 3,FGFR-3,2.7.10.1,CD333,FGFR3,JTK4,

Tissue Specificity: Expressed in brain, kidney and testis. Very low or no expression in spleen, heart, and muscle. In 20- to 22- week old fetuses it is expressed at high level in kidney, lung, small intestine and brain, and to a lower degree in spleen, liver, and muscle. Isoform 2 is detected in epithelial cells. Isoform 1 is not detected in epithelial cells. Isoform 1 and isoform 2 are detected in fibroblastic cells. .

Molecular Weight: 103 kDa

UniProt: P22607

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding