Fibrillarin antibody

Catalog No. ABIN7604848

The Rabbit Monoclonal anti-Fibrillarin antibody has been validated for WB, IHC, IP, IF, ICC and FACS. It is suitable to detect Fibrillarin in samples from Human, Rat and Mouse.

Quick Overview for Fibrillarin antibody (ABIN7604848)

Target: Fibrillarin (FBL)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Fibrillarin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: DIO-6

Product Details anti-Fibrillarin Antibody

Purpose: Anti-Fibrillarin FBL Rabbit Monoclonal Antibody

Characteristics: Anti-Fibrillarin FBL Rabbit Monoclonal Antibody (ABIN7604848). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Fibrillarin

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:100
ICC/IF 1:50-1:100
IP :
1:30
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Fibrillarin

Target: Fibrillarin (FBL)

Alternative Name: FBL

Background:

Synonyms: rRNA 2'-O-methyltransferase fibrillarin,2.1.1.-,34 kDa nucleolar scleroderma antigen,Histone-glutamine methyltransferase,FBL,FIB1, FLRN,

Tissue Specificity: In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

Molecular Weight: 70 kDa

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process