Geminin antibody

Catalog No. ABIN7604960

This anti-Geminin antibody is a Rabbit Monoclonal antibody detecting Geminin in WB, IHC, IF and ICC. Suitable for Human.

Quick Overview for Geminin antibody (ABIN7604960)

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Geminin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AEGO-7

Product Details anti-Geminin Antibody

Purpose: Anti-Geminin Monoclonal Antibody

Characteristics: Anti-Geminin Monoclonal Antibody (ABIN7604960). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Geminin Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Alternative Name: GMNN

Background:

Synonyms: Hyaluronan and proteoglycan link protein 1,Cartilage-linking protein 1,Cartilage-link protein,Proteoglycan link protein,HAPLN1,CRTL1,

Tissue Specificity: Widely expressed. Weakly expressed in the brain. .

Molecular Weight: 63 kDa

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication