HMGCR antibody

Catalog No. ABIN7605138

This Rabbit Monoclonal antibody specifically detects HMGCR in WB and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for HMGCR antibody (ABIN7605138)

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HMGCR antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: AOCC-8

Product Details anti-HMGCR Antibody

Purpose: Anti-HMGCR/Hmg Coa Reductase Rabbit Monoclonal Antibody

Characteristics: Anti-HMGCR/Hmg Coa Reductase Rabbit Monoclonal Antibody (ABIN7605138). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human HMGCR

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR

Background:

Synonyms: 3-hydroxy-3-methylglutaryl-coenzyme A reductase,HMG-CoA reductase,1.1.1.34,HMGCR,

Tissue Specificity: Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.

Molecular Weight: 85 kDa

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha