IFNAR1 antibody

Catalog No. ABIN7605218

This anti-IFNAR1 antibody is a Rabbit Monoclonal antibody detecting IFNAR1 in WB, FACS and IP. Suitable for Human.

Quick Overview for IFNAR1 antibody (ABIN7605218)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFNAR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: DDC-9

Product Details anti-IFNAR1 Antibody

Purpose: Anti-IFNAR1/Beta R1 Rabbit Monoclonal Antibody

Characteristics: Anti-IFNAR1/Beta R1 Rabbit Monoclonal Antibody (ABIN7605218). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human IFNAR1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IP 1:50
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: IFNAR1

Background:

Synonyms: Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,CRF2-1,Type I interferon receptor 1,IFNAR1,IFNAR,

Tissue Specificity: IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. .

Molecular Weight: 62 kDa

UniProt: P17181

Pathways: JAK-STAT Signaling, Hepatitis C