IL7R antibody

Catalog No. ABIN7605261

This Rabbit Monoclonal antibody specifically detects IL7R in FACS and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IL7R antibody (ABIN7605261)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB)

Clone: 22I71

Product Details anti-IL7R Antibody

Purpose: Anti-IL7R alpha/CD127 Rabbit Monoclonal Antibody

Characteristics: Anti-IL7R alpha/ Rabbit Monoclonal Antibody (ABIN7605261). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human IL7R alpha/CD127

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
FC 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: IL7R

Background:

Synonyms: CD276 antigen,4Ig-B7-H3,B7 homolog 3,B7-H3,Costimulatory molecule,CD276,CD276,B7H3,PSEC0249, UNQ309/PRO352,

Tissue Specificity: Ubiquitous but not detectable in peripheral blood lymphocytes or granulocytes. Weakly expressed in resting monocytes. Expressed in dendritic cells derived from monocytes. Expressed in epithelial cells of sinonasal tissue. Expressed in extravillous trophoblast cells and Hofbauer cells of the first trimester placenta and term placenta. .

Molecular Weight: 75 kDa

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size