MYD88 antibody

Catalog No. ABIN7605633

This Rabbit Monoclonal antibody specifically detects MYD88 in WB, IHC, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for MYD88 antibody (ABIN7605633)

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MYD88 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: FED-13

Product Details anti-MYD88 Antibody

Purpose: Anti-MyD88 Monoclonal Antibody

Characteristics: Anti-MyD88 Monoclonal Antibody (ABIN7605633). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human MyD88 Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF- Kappa B and subsequent regulation of immune and inflammatory genes.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Alternative Name: MYD88

Background:

Synonyms: Signal transducer and activator of transcription 3,Acute-phase response factor,STAT3,APRF,

Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Molecular Weight: 56 kDa

UniProt: Q99836

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades