NEDD4-2 antibody

Catalog No. ABIN7605686

The Rabbit Monoclonal anti-NEDD4-2 antibody (Clone GOA-14) (ABIN7605686) specifically detects NEDD4-2 in WB and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NEDD4-2 antibody (ABIN7605686)

Target: NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NEDD4-2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: GOA-14

Product Details anti-NEDD4-2 Antibody

Purpose: Anti-NEDD4-2 NEDD4L Rabbit Monoclonal Antibody

Characteristics: Anti-NEDD4-2 NEDD4L Rabbit Monoclonal Antibody (ABIN7605686). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human NEDD4-2

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for NEDD4-2

Target: NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))

Alternative Name: NEDD4L

Background:

Synonyms: E3 ubiquitin-protein ligase NEDD4-like,6.3.2.-,NEDD4.2,Nedd4-2,NEDD4L,KIAA0439, NEDL3,

Tissue Specificity: Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597). Expressed in melanocytes (PubMed:23999003). .

Molecular Weight: 130 kDa

Pathways: Negative Regulation of Transporter Activity