Survivin antibody

Catalog No. ABIN7606418

The Rabbit Monoclonal anti-Survivin antibody (Clone DGD-2) (ABIN7606418) specifically detects Survivin in WB, IHC and IP. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Survivin antibody (ABIN7606418)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DGD-2

Product Details anti-Survivin Antibody

Purpose: Anti-Survivin Birc5 Rabbit Monoclonal Antibody

Characteristics: Anti-Survivin Birc5 Rabbit Monoclonal Antibody (ABIN7606418). Tested in WB, IHC, IP applications. This antibody reacts with Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Survivin

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
IP 1:30

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Birc5

Background:

Synonyms: Baculoviral IAP repeat-containing protein 5,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,TIAP,Birc5,Api4, Iap4,

Tissue Specificity: Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines. .

Molecular Weight: 125 kDa

UniProt: O70201

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding