TdT antibody

Catalog No. ABIN7606472

The Rabbit Monoclonal anti-TdT antibody (Clone AFHA-4) (ABIN7606472) specifically detects TdT in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TdT antibody (ABIN7606472)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TdT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AFHA-4

Product Details anti-TdT Antibody

Purpose: Anti-TDT DNTT Monoclonal Antibody

Characteristics: Anti-TDT DNTT Monoclonal Antibody (ABIN7606472). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TDT Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Alternative Name: DNTT

Background:

Synonyms: Drebrin,Developmentally-regulated brain protein,DBN1,D0S117E,

Tissue Specificity: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level). .

Molecular Weight: 10 kDa

UniProt: P04053

Pathways: DNA Damage Repair