TRF2 antibody

Catalog No. ABIN7606575

This Rabbit Monoclonal antibody specifically detects TRF2 in WB, IHC, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for TRF2 antibody (ABIN7606575)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AFOB-20

Product Details anti-TRF2 Antibody

Purpose: Anti-TRF2 Monoclonal Antibody

Characteristics: Anti-TRF2 Monoclonal Antibody (ABIN7606575). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TRF2 Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2

Background:

Synonyms: DNA-dependent protein kinase catalytic subunit,DNA-PK catalytic subunit,DNA-PKcs,2.7.11.1,DNPK1,p460,PRKDC,HYRC, HYRC1,

Tissue Specificity: Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.

Molecular Weight: 42 kDa

UniProt: Q15554

Pathways: Cell Division Cycle, Telomere Maintenance