Recombinant TSH receptor antibody

Catalog No. ABIN7852035

The Human Chimeric anti-TSH receptor antibody is suitable to detect TSH receptor in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant TSH receptor antibody (ABIN7852035)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This TSH receptor antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1C8

Product Details anti-TSH receptor Antibody

Purpose: Anti-TSHR antibody(1C8), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

UniProt: P16473

Pathways: Thyroid Hormone Synthesis