Recombinant CXCR4 antibody (Biotin)

Catalog No. ABIN7851795

The Human Chimeric anti-CXCR4 antibody is suitable to detect CXCR4 in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant CXCR4 antibody (Biotin) (ABIN7851795)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This CXCR4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: DMC680

Product Details anti-CXCR4 Antibody (Biotin)

Purpose: Biotinylated Anti-CXCR4 antibody(DMC680), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

UniProt: P61073, A0A0U3FJG0, A0A0U3GXA9

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events