DKK1 antibody (Biotin)

Catalog No. ABIN7851565

The Biotin-conjugated Rabbit Monoclonal anti-DKK1 antibody (Clone DM210) (ABIN7851565) specifically detects DKK1 in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for DKK1 antibody (Biotin) (ABIN7851565)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DKK1 antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: DM210

Product Details anti-DKK1 Antibody (Biotin)

Purpose: Biotinylated Anti-DKK1 antibody(DM210), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: DKK1

Background: This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.

UniProt: O94907

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation