MICB antibody (Biotin)

Catalog No. ABIN7608306

Product Details anti-MICB Antibody (Biotin)

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MICB antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Purpose: Biotinylated Anti-MICB antibody(DM168), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Clone: DM168

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB (MICB Products)

Background: This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response