Abeta 1-40 antibody

Catalog No. ABIN729328

This Rabbit Polyclonal antibody specifically detects Abeta 1-40 in WB, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Abeta 1-40 antibody (ABIN729328)

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Abeta 1-40 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Abeta 1-40 Antibody

Purpose: beta-Amyloid 1-40 (CT) Polyclonal Antibody

Cross-Reactivity: Chicken, Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta-Amyloid 1-40

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Abeta 1-40

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Alternative Name: beta-Amyloid 1-40

Background:

Synonyms: beta Amyloid1-40, beta Amyloid 1-40, beta-Amyloid 1-40, Amyloid 1-40, P340, A4, AAA, ABETA, ABPP, AD1, Alzheimers Disease Amyloid Protein, Amyloid B, Amyloid Beta A4 Protein Precursor, Amyloid Beta, Amyloid of Aging and Alzheimer Disease, APP, APPI, B Amyloid, Beta APP, Cerebral Vascular Amyloid Peptide, CTFgamma, CVAP, PN II, PN2, PreA4, Protease nexin II, A beta, A4_HUMAN.

Background: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

Molecular Weight: 4.3kDa

Gene ID: 351