SNCA antibody (AA 1-140)
Quick Overview for SNCA antibody (AA 1-140) (ABIN730393)
Target
See all SNCA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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    - 
                                            Binding Specificity
- AA 1-140
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                                            Cross-Reactivity
- Human, Mouse, Rat
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                                            Purification
- Purified by Protein A.
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                                            Immunogen
- Recombinant full length Alpha-Synuclein
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                                            Isotype
- IgG
 
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    - 
                                            Application Notes
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
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                                            Restrictions
- For Research Use only
 
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    - 
                                            Format
- Liquid
- 
                                            Concentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Preservative
- ProClin
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                                            Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            Storage
- 4 °C,-20 °C
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                                            Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            Expiry Date
- 12 months
 
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    - SNCA (Synuclein, alpha (SNCA))
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                                            Alternative Name
- Alpha-Synuclein
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                                            Background
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                        Synonyms: PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, SNCA Background: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. 
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                                            Gene ID
- 6622
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                                            UniProt
- P37840
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                                            Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
 Target
- 
                    
 
                                     
                                     
                                    