Reelin antibody

Catalog No. ABIN731348

The Rabbit Polyclonal anti-Reelin antibody is suitable to detect Reelin in samples from Human. It has been validated for IHC (p), IF and IHC (fro).

Quick Overview for Reelin antibody (ABIN731348)

Target: Reelin (RELN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reelin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Reelin Antibody

Purpose: Reelin Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RELN

Isotype: IgG

Application Details

Application Notes: IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Reelin

Target: Reelin (RELN)

Alternative Name: Reln/Reelin

Background:

Synonyms: RL, ETL7, LIS2, PRO1598, Reelin, RELN

Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Gene ID: 5649

UniProt: P78509

Pathways: Synaptic Membrane