BARX1 antibody (AA 155-254) (CF®594)

Catalog No. ABIN7649992

This Mouse Monoclonal antibody specifically detects BARX1 in IHC and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for BARX1 antibody (AA 155-254) (CF®594) (ABIN7649992)

Target: BARX1 (BARX Homeobox 1 (BARX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BARX1 antibody is conjugated to CF®594

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BARX1-2759

Product Details anti-BARX1 Antibody (CF®594)

Binding Specificity: AA 155-254

Purpose: BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)(BARX1/2759), CF594 conjugate

Characteristics: BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes hepatocellular carcinoma cell (HCC) migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human BARX1 protein (around aa 155-254)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HepG2 cell lysate. Pancreas.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for BARX1

Target: BARX1 (BARX Homeobox 1 (BARX1))

Alternative Name: BARX1

Background:

Synonyms: BARX1, Homeobox protein BarH-like 1, BARX homeobox 1

Gene Symbol: BARX1

Molecular Weight: 24 kDa

Gene ID: 56033

Pathways: Sensory Perception of Sound