FGF23 antibody (CF®740)

Catalog No. ABIN7654034

The Mouse Monoclonal anti-FGF23 antibody has been validated for . It is suitable to detect FGF23 in samples from Human.

Quick Overview for FGF23 antibody (CF®740) (ABIN7654034)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF23 antibody is conjugated to CF®740

Application: Please inquire

Clone: FGF23-638

Product Details anti-FGF23 Antibody (CF®740)

Purpose: FGF23(FGF23/638), CF740 conjugate

Characteristics: Fibroblast growth factor-1 (FGF-1, acidic FGF) and fibroblast growth factor-2 (FGF-2, basic FGF) are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin.Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure. They are capable of transforming cultured cells when overexpressed by transfection. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human FGF23 protein

Isotype: IgG1, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Human PBL cells or brain tumors

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: FGF23

Background:

Synonyms: ADHR, FGF-23, FGFN, Fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, Tumor-derived hypophosphatemia-inducing factor

Gene Symbol: FGF23

Molecular Weight: 12-32 kDa

Gene ID: 8074

UniProt: Q9GZV9

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion