Keratin 3 antibody (CF®568)

Catalog No. ABIN7656170

The Mouse Monoclonal anti-Keratin 3 antibody has been validated for IHC and IHC (fp). It is suitable to detect Keratin 3 in samples from Human.

Quick Overview for Keratin 3 antibody (CF®568) (ABIN7656170)

Target: Keratin 3 (KRT3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Keratin 3 antibody is conjugated to CF®568

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: KRT3-2130

Product Details anti-Keratin 3 Antibody (CF®568)

Purpose: Cytokeratin 3 (KRT3) (Corneal Epithelial Marker)(KRT3/2130), CF568 conjugate

Characteristics: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins, which are arranged in pairs of heterotypic keratin chains co-expressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human KRT3 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: A431 cells. Cornea or Skin.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Keratin 3

Target: Keratin 3 (KRT3)

Alternative Name: Keratin 3

Background:

Synonyms: 65 kDa cytokeratin, CK3, Cytokeratin-3, K3, Keratin type II Cytoskeletal-3, Keratin-3, KRT3

Gene Symbol: KRT3

Tissue Expression: Eye

Molecular Weight: 65 kDa

Gene ID: 38550

UniProt: P12035