Keratin 3 antibody (C-Term)

Catalog No. ABIN2788204

The Rabbit Polyclonal anti-Keratin 3 antibody is suitable to detect Keratin 3 in samples from Human and Rabbit. It has been validated for WB.

Quick Overview for Keratin 3 antibody (C-Term) (ABIN2788204)

Target: Keratin 3 (KRT3)

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 3 Antibody

Binding Specificity: C-Term

Purpose: KRT3 Antibody - C-terminal region

Sequence: GSSGFSGGSG FGSISGARYG VSGGGFSSAS NRGGSIKFSQ SSQSSQRYSR

Predicted Reactivity: Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against KRT3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59767-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 3

Target: Keratin 3 (KRT3)

Alternative Name: KRT3

Background:

Background Information: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: Keratin 3

Alternative Symbols: K3, CK3, MECD2

Protein Name: Keratin, type II cytoskeletal 3

Molecular Weight: 64kDa

Gene ID: 3850

NCBI Accession: NP_476429

UniProt: P12035