MAGEA4 antibody

Catalog No. ABIN7656760

This Mouse Monoclonal antibody specifically detects MAGEA4 in IHC and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for MAGEA4 antibody (ABIN7656760)

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPTC-MAGEA4-1

Product Details anti-MAGEA4 Antibody

Purpose: Melanoma Antigen Family A, 4 / MAGEA4(CPTC-MAGEA4-1)

Characteristics: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human MAGEA4 protein

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HepG2 cell lysate, melanoma, testes and placenta.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4

Background:

Synonyms: CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, cancer/testis antigen 1.4, Melanoma-associated antigen 4

Gene Symbol: MAGEA4

Tissue Expression: Placenta|Testis

Molecular Weight: 45-50 kDa

Gene ID: 4103

UniProt: P43358