Tumor Protein p73 antibody (CF®594)

Catalog No. ABIN7661426

The Mouse Monoclonal anti-Tumor Protein p73 antibody has been validated for IHC and IHC (fp). It is suitable to detect Tumor Protein p73 in samples from Human.

Quick Overview for Tumor Protein p73 antibody (CF®594) (ABIN7661426)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tumor Protein p73 antibody is conjugated to CF®594

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: P73-2531

Product Details anti-Tumor Protein p73 Antibody (CF®594)

Purpose: p73 (Tumor Suppressor)(P73/2531), CF594 conjugate

Characteristics: p73 shares considerable sequence similarity with the widely-studied tumor suppressor gene p53. The p73 gene maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, unlike p53, p73 does not appear to be activated by DNA damaging agents. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human TP73 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HeLa, Jurkat, HEK293 cell lysates. Human kidney or bladder carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: p73

Background:

Synonyms: p53-like transcription factor, p53-related protein, p73, TP73, Tumor protein p73

Gene Symbol: TP73

Molecular Weight: 73 kDa

Gene ID: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus