TACSTD2 antibody (AA 31-274) (CF®594)

Catalog No. ABIN7661450

The Mouse Monoclonal anti-TACSTD2 antibody has been validated for IHC and IHC (fp). It is suitable to detect TACSTD2 in samples from Human.

Quick Overview for TACSTD2 antibody (AA 31-274) (CF®594) (ABIN7661450)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TACSTD2 antibody is conjugated to CF®594

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: TACSTD2-2153

Product Details anti-TACSTD2 Antibody (CF®594)

Binding Specificity: AA 31-274

Purpose: TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2153), CF594 conjugate

Characteristics: TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human TACSTD2 protein (around aa 31-274)

Isotype: IgG1, kappa

Application Details

Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Comment:

Positive Control: HT29 cells. Breast or Colon Carcinoma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for TACSTD2

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Alternative Name: TACSTD2

Background:

Synonyms: Cell surface glycoprotein Trop-2,Membrane Component Chromosome 1, Surface Marker 1 (M1S1),Pancreatic Carcinoma Marker Protein GA733-1,TROP2,Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)

Gene Symbol: TACSTD2

Tissue Expression: Cornea|Epithelial cells|Placenta

Molecular Weight: 40 kDa

Gene ID: 4070

UniProt: P09758