ADAM17 antibody (AA 215-314) (APC)

Catalog No. ABIN7662285

The Mouse Monoclonal anti-ADAM17 antibody has been validated for WB, FACS and IF. It is suitable to detect ADAM17 in samples from Human.

Quick Overview for ADAM17 antibody (AA 215-314) (APC) (ABIN7662285)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADAM17 antibody is conjugated to APC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Cell Culture Grade

Clone: 1F6

Product Details anti-ADAM17 Antibody (APC)

Binding Specificity: AA 215-314

Purpose: APC conjugated mouse monoclonal antibody raised against a partial recombinant ADAM17.This product is a Cell Culture Grade Antibody.

Sequence: RADPDPMKNT CKLLVVADHR FYRYMGRGEE STTTNYLIEL IDRVDDIYRN TSWDNAGFKG YGIQIEQIRI LKSPQEVKPG EKHYNMAKSY PNEEKDAWDV

Cross-Reactivity: Human

Characteristics: Cell culture grade monoclonal antibodies are obtained by purifying hybridoma culture medium with Protein A purification.
These antibodies can completely eliminate any contamination of mice and no mice are sacrificed during the process.
Therefore, such antibodies can have high affinity, high purity, and no contamination. Antibody Reactive Against Recombinant Protein.

Purification: Cell Culture Production with Protein A purification

Immunogen: ADAM17 (NP_003174.3, 215 a.a. ~ 314 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM17

Background:

gene_description: ADAM metallopeptidase domain 17

gene_alias: CD156b|MGC71942|TACE|cSVP

Gene ID: 6868

NCBI Accession: NM_003183

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus