CD180 antibody

Catalog No. ABIN7669988

The Mouse Monoclonal anti-CD180 antibody (Clone G28-8) (ABIN7669988) specifically detects CD180 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD180 antibody (ABIN7669988)

Target: CD180 (CD180 Molecule (CD180))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD180 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: G28-8

Product Details anti-CD180 Antibody

Purpose: Purified Anti-Human CD180 Antibody[G28-8]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD180

Target: CD180 (CD180 Molecule (CD180))

Alternative Name: CD180

Background: LY64,RP105,CD180,Ly78,CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades