CCR3 antibody

Catalog No. ABIN7670041

The Mouse Monoclonal anti-CCR3 antibody is suitable to detect CCR3 in samples from Human. It has been validated for FACS.

Quick Overview for CCR3 antibody (ABIN7670041)

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5E8

Product Details anti-CCR3 Antibody

Purpose: Purified Anti-Human CD193 Antibody[5E8]

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CCR3

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Alternative Name: CD193

Background: CKR,B-lymphocyte antigen CD,MIP1-alpha receptor like,Differentiation antigen CD,C-C chemokine receptor type,Neural cell adhesion molecule,CMKBR,N-CAM,CC-CKR,CC CKR,CCR3,CC-CKR-3,CD193,CKR3,CMKBR3,B-lymphocyte antigen CD19,C-C chemokine receptor type 3,CC CKR3,CCR,Cd19,Differentiation antigen CD19,eotaxin receptor,MIP1-alpha receptor like-2,NCAM,NCAM1,NCAM-1,N-CAM-1,Neural cell adhesion molecule 1,C-C CKR-3,C-C motif chemokine receptor 3,CD_antigen: CD193,cluster of differentiation 193,Eosinophil eotaxin receptor,The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

UniProt: P51677