CD20 antibody

Catalog No. ABIN7670103

This Mouse Monoclonal antibody specifically detects CD20 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD20 antibody (ABIN7670103)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD20 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: Rituximab

Product Details anti-CD20 Antibody

Purpose: Purified Anti-Human CD20 Antibody[Rituximab]

Purification: >98%, Protein A/G purified

Immunogen: Recombinant Human CD20 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: PBS, pH 7.2. Contains 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Alternative Name: CD20/MS4A1

Background: LEU,CVID,B-lymphocyte antigen CD,Leukocyte surface antigen Leu,B-lymphocyte surface antigen B,Membrane-spanning 4-domains subfamily A member,MS4A1,B1,Bp35,CD20,CVID5,LEU-16,MS4A2,S7,B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1,Bp35,Ly-44,APY,ATOPY,B lymphocyte antigen CD20,B Lymphocyte Cell Surface Antigen B1,B-lymphocyte cell-surface antigen B1,Bp 35,CD 20,CD20 antigen,CD20 receptor,Fc epsilon receptor I beta chain,Fc Fragment of IgE high affinity I receptor for beta polypeptide,FCER1B,High affinity immunoglobulin epsilon receptor subunit beta,IgE Fc receptor subunit beta,IGEL,IGER,IGHER,LEU 16,LEU16,leukocyte surface antigen Leu 16,Ly44,Membrane spanning 4 domains A1,Membrane spanning 4 domains subfamily A member 2,MGC3969,CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naive and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65 % aa sequence identity between human and mouse CD20.

UniProt: P11836