PD-1 antibody

Catalog No. ABIN7670108

This anti-PD-1 antibody is a Rabbit Monoclonal antibody detecting PD-1 in FACS. Suitable for Human.

Quick Overview for PD-1 antibody (ABIN7670108)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5C4-B8 (Nivolumab)

Product Details anti-PD-1 Antibody

Purpose: Purified Anti-Human CD279 Antibody[5C4.B8 (Nivolumab)]

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: CD279/PD-1

Background: PDCD1,PD1,Protein PD-1,hPD-1,rogrammed Death-1 (PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses . Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or down-regulate T cell activation (CTLA-4 and PD-1).

UniProt: Q15116

Pathways: Cancer Immune Checkpoints