Interleukin 17a antibody

Catalog No. ABIN7670182

The Mouse Monoclonal anti-Interleukin 17a antibody is suitable to detect Interleukin 17a in samples from Mouse. It has been validated for ICFC.

Quick Overview for Interleukin 17a antibody (ABIN7670182)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: Intracellular Flow Cytometry (ICFC)

Clone: 17F3

Product Details anti-Interleukin 17a Antibody

Purpose: AF/LE Purified Anti-Mouse IL-17A Antibody[17F3]

Endotoxin Level: Low Endotoxin

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Preservative: Azide free

Handling Advice: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A

Background: Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

UniProt: Q62386