Annexin a1 antibody

Catalog No. ABIN7670503

This anti-Annexin a1 antibody is a Rabbit Polyclonal antibody detecting Annexin a1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for Annexin a1 antibody (ABIN7670503)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin a1 Antibody

Purpose: Annexin A1 Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Annexin A1 protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: WB 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1

Background: ANX,Annexin I (lipocortin I),AnnexinA1,AnnexinI,ANX 1,ANX A1,ANXA 1,ANXA1 protein,CalpactinII,Chromobindin9,HGNC:533,Lipocortin 1,lipocortin I,ANX1,LPC1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 inhibitory protein,p35,Lipocortin1,LipocortinI,LPC 1,LPC,ANXA,Annexin A,ANXA1,ANX1,LPC1,Annexin 1,Calpactin 2,Chromobindin 9,Annexin-1,Chromobindin-9,p35,Calpactin-2,Annexin A1,Annexin I,Calpactin II,Lipocortin I,Phospholipase A2 Inhibitory Protein,Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells.Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton.Has high affinity for Ca2+ and can bind up to eight Ca2+ ions. Displays Ca2+-dependent binding to phospholipid membranes. Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton.

Molecular Weight:

Calculated MW: 38 kDa

ObservedMW: 35 kDa

UniProt: P04083

Pathways: Hormone Transport