Annexin a1 antibody (AA 144-248)

Catalog No. ABIN1098115

This Mouse Monoclonal antibody specifically detects Annexin a1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Monkey. It has been mentioned in 2+ publications

Quick Overview for Annexin a1 antibody (AA 144-248) (ABIN1098115)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2F1

Product Details anti-Annexin a1 Antibody

Binding Specificity: AA 144-248

Purpose: ANXA1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ANXA1 (AA: 144-248 ) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Annexin a1 antibody (ABIN1098115)

Nair, Hande, Lim: "Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage." in: Cancer letters, Vol. 294, Issue 1, pp. 111-7, (2010) (PubMed).

Li, Shen, Huang, Huang, Wang, Wu: "Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma." in: Pathology, Vol. 42, Issue 1, pp. 43-9, (2009) (PubMed).

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: ANXA1

Background: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Molecular Weight: 38.7 kDa

UniProt: P04083

Pathways: Hormone Transport