Annexin a1 antibody (AA 144-248)

Catalog No. ABIN1098115

Product Details anti-Annexin a1 Antibody

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Binding Specificity: AA 144-248

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: Purified recombinant fragment of human ANXA1 (AA 144-248 ) expressed in E. coli.

Clone: 2F1

Isotype: IgG1

Application Details

Application Notes: Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C or at -20 °C for long term.

References for anti-Annexin a1 antibody (ABIN1098115)

Nair, Hande, Lim: "Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage." in: Cancer letters, Vol. 294, Issue 1, pp. 111-7, (2010) (PubMed).

Li, Shen, Huang, Huang, Wang, Wu: "Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma." in: Pathology, Vol. 42, Issue 1, pp. 43-9, (2009) (PubMed).

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: ANXA1 (ANXA1 Products)

Synonyms: anx1a antibody, anxa1 antibody, wu:fa01d11 antibody, wu:fa05d11 antibody, wu:fk69h01 antibody, MGC64363 antibody, anx1 antibody, lpc1 antibody, MGC89164 antibody, ANXA1 antibody, ANX1 antibody, LPC1 antibody, p35 antibody, Anx-1 antibody, Anx-A1 antibody, C430014K04Rik antibody, Lpc-1 antibody, Lpc1 antibody, Anx1 antibody, annexin A1a antibody, annexin A1 antibody, annexin A1 L homeolog antibody, Annexin A1 antibody, anxa1a antibody, anxa1 antibody, anxa1.L antibody, ANXA1 antibody, LOC100335033 antibody, Anxa1 antibody

Background: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Molecular Weight: 38.7 kDa

Gene ID: 301

HGNC: 301

Pathways: Hormone Transport