Liver Arginase antibody

Catalog No. ABIN7670538

The Rabbit Polyclonal anti-Liver Arginase antibody has been validated for WB and ELISA. It is suitable to detect Liver Arginase in samples from Rat and Mouse.

Quick Overview for Liver Arginase antibody (ABIN7670538)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Liver Arginase Antibody

Purpose: Arginase 1/ARG1 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Mouse Arginase 1/ARG1 protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arginase 1

Background: Arg1,Arginase-1,Liver-type arginase,Type I arginase,Arginase is the focal enzyme of the urea cycle hydrolysing l-arginine to urea and l-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of l-arginine to l-ornithine and the formation of polyamines and l-proline,which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals,Arginase 1 (ARG1) also known as Arginase,liver,which functions in the urea cycle,and is located primarily in the cytoplasm of the liver. The second isozyme,Arginase II,has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body,with most abundance in the kidney and prostate. It may be found at lower levels in macrophages,lactating mammary glands,and brain.

Molecular Weight:

Calculated MW: 34kDa

ObservedMW: 40kDa

UniProt: Q61176

Pathways: Cellular Response to Molecule of Bacterial Origin