C3 antibody

Catalog No. ABIN7670579

This Rabbit Polyclonal antibody specifically detects C3 in ELISA. It exhibits reactivity toward Pig.

Quick Overview for C3 antibody (ABIN7670579)

Target: C3 (Complement Component 3 (C3))

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3 antibody is un-conjugated

Application: ELISA

Product Details anti-C3 Antibody

Purpose: Complement C3 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Pig Complement C3 protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for C3

Target: C3 (Complement Component 3 (C3))

Alternative Name: Complement C3

Background: ASP,CPAMD1,AHUS5,ARMD9,C3a,C3b,The complement system is an important effector which bridges the innate and adaptive immune systems . The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. Human C3, composed of α and β chains (115 and 75 kDa, respectively). Activation of C3 convertase cleaves the C3 α-subunit to generate C3a, which acts as an anaphylatoxin to mediate the local inflammatory response. C3b is further cleaved into iC3b, C3c, C3dg, and C3f.

UniProt: P01025

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling