EPO antibody

Catalog No. ABIN7670597

This Rat Monoclonal antibody specifically detects EPO in ELISA (Detection). It exhibits reactivity toward Mouse.

Quick Overview for EPO antibody (ABIN7670597)

Target: EPO (Erythropoietin (EPO))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: ELISA (Detection)

Clone: 7G7

Product Details anti-EPO Antibody

Purpose: Erythropoietin/EPO Monoclonal Antibody(Detector)

Purification: Protein A/G Purification

Immunogen: Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli

Isotype: IgM

Application Details

Application Notes: ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: Erythropoietin/EPO

Target Type: Hormone

Background: MGC,ECYT,MVCD,Hematopoietin,Hemopoietin,ECYT5,EP,epoetin,Erythropoietin,MGC138142,MVCD2,Epo,This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

UniProt: P07321

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity