FETUB antibody

Catalog No. ABIN7670603

This Rabbit Polyclonal antibody specifically detects FETUB in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for FETUB antibody (ABIN7670603)

Target: FETUB (Fetuin B (FETUB))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FETUB antibody is un-conjugated

Application: ELISA

Product Details anti-FETUB Antibody

Purpose: Fetuin B Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Mouse Fetuin B protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for FETUB

Target: FETUB (Fetuin B (FETUB))

Alternative Name: Fetuin B

Background: 2310011O17Rik,AI255764,D17980,Gugu,Fetub,Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as alpha 2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acute-phase protein. Normal circulating levels of Fetuin A in adults (300?600 μg/mL) fall significantly (30?50 % ) during injury and infection. Fetuin B is a newer member whose function is not fully characterized. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were down?regulated during the acute phase in inflammation-induced rats. However, they share only 20 % amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males.

UniProt: Q9QXC1